NIPT (Non-Invasive Prenatal Test)

The NIPT is an examination where blood from the pregnant woman is taken and examined.

The laboratory examines the DNA in the blood for chromosomal abnormalities, which enables us to determine whether the child has Down's, Edward's or Patau's syndrome. The blood from pregnant women contains DNA from the placenta and DNA from the mother. The DNA from the placenta is almost always the same as the DNA of the child.

The NIPT can be taken from 11 weeks into the pregnancy term.

Scientific study

From 1 April 2017, all pregnant women in the Netherlands can opt to take the NIPT but only if you participate in a scientific study (TRIDENT-2).
Why a study? Other countries have more experience with NIPT than the Netherlands. In these countries, the NIPT is regarded as a highly reliable test. The Minister would now like to investigate whether the test also works well in the Netherlands.
And what women think about the NIPT. If you opt to take the NIPT, you grant the researchers permission to use your data. You will be asked to sign a permission form for this.
For more on this scientific study and what is done with your data, please go to: Meer over NIPT.

Incidental findings with the NIPT

The laboratory can also find other chromosomal abnormalities other than Down's, Edward's and Patau's syndrome with the child, in the placenta and extremely rarely, with the pregnant woman herself. These are known as incidental findings.
The decision whether these incidental findings should be revealed is yours alone. There are various sorts of incidental findings:
from very severe to less severe. In order to be sure which incidental finding we are dealing with, a follow-up examination will be necessary, mostly an amniocentesis or a chorion villus sampling. Out of all 1000 pregnant women who opt for the NIPT, approximately 4 women are informed about an incidental finding.


Information on payment of the NIPT can be found on NIPT betalen.
For more information on the NIPT and incidental findings, please go to: Onderzoek van mijn ongeboren kind

When a pregnant woman does not qualify for the NIPT (Trident-2)

When a pregnant woman due to exclusion criteria (no (BSN) citizen service number/No Dutch health insurence, underage) does not qualify for the NIPT (Trident-2), Echopunt offers the possibility of having the NIPT (VERISEQ V2-test) performed via Belgium. The pregnant woman can have her blood taken at Echopunt, which is then sent to a laboratory in Brussels. For more information